MyBioSource.com's MOUSE ANTI CHICKEN INTERFERON ALPHA is a Mouse monoclonal antibody. The MOUSE ANTI CHICKEN INTERFERON ALPHA Antibody was generated using IFNA3, Interferon, and Miscellaneous as the antigen. It reacts with Chicken/Bird. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
MBS212785 recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. MBS212785 does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha